Antioxidant and nitric oxide synthase activation properties of Ganoderma applanatum.

نویسندگان

  • Krishnendu Acharya
  • Parinita Yonzone
  • Manjula Rai
  • Acharya Rupa
چکیده

In vitro evaluation of antioxidant activities of Ganoderma applanatum showed significant inhibition of lipid peroxidation, and potent hydroxyl radical scavenging activity when compared with standard drug catechin. IC50 values of crude, boiled and ethanolic extracts of G. applanatum were 604.8, 624 and 267 microg/ml, respectively in case of hydroxyl radical scavenging activity, and 441, 520.5 and 166.16 microg/ml, respectively in case of lipid peroxidation. Furthermore, crude, boiled and ethanolic extracts also increased significantly nitric oxide production (156.67, 121.88 and 742 pmole/mg dry wt/hr, respectively) over the control. The results of present investigation revealed that G. applanatum have potential therapeutic use.

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عنوان ژورنال:
  • Indian journal of experimental biology

دوره 43 10  شماره 

صفحات  -

تاریخ انتشار 2005